CD81 抗体
Quick Overview for CD81 抗体 (ABIN614802)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
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交叉反应 (详细)
- Species reactivity (tested):Human, Feline (Cat), Rabbit
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure by SDS-PAGE
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免疫原
- MOLT-4 (human T-ALL cell line)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).
: "
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Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).
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- CD81
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别名
- CD81 / TAPA1
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背景
- CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1
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基因ID
- 975
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NCBI登录号
- NP_004347
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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