SKIL 抗体 (AA 420-684)
Our Local Distributor
北京 101111
Quick Overview for SKIL 抗体 (AA 420-684) (ABIN6147811)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 420-684
-
序列
- SQSKELTKTE ASKSISRQSE KAHSSGKLQK TVSYPDVSLE EQEKMDLKTS RELCSRLDAS ISNNSTSKRK SESATCNLVR DINKVGIGLV AAASSPLLVK DVICEDDKGK IMEEVMRTYL KQQEKLNLIL QKKQQLQMEV KMLSSSKSMK ELTEEQQNLQ KELESLQNEH AQRMEEFYVE QKDLEKKLEQ IMKQKCTCDS NLEKDKEAEY AGQLAELRQR LDHAEADRQE LQDELRQERE ARQKLEMMIK ELKLQILKSS KTAKE
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- SKIL (SKI-Like Oncogene (SKIL))
-
别名
- SKIL
-
背景
- The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,SKIL,SNO,SnoA,SnoI,SnoN,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Target gene,SKIL
-
分子量
- 44 kDa/46 kDa/71 kDa/74 kDa/76 kDa
-
基因ID
- 6498
-
UniProt
- P12757
-
途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-