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SAV1 抗体 (AA 1-210)

This anti-SAV1 antibody is a 兔 多克隆 antibody detecting SAV1 in WB. Suitable for 人.
产品编号 ABIN6147400
发货至: 中国

Quick Overview for SAV1 抗体 (AA 1-210) (ABIN6147400)

抗原

See all SAV1 抗体
SAV1 (Salvador Homolog 1 (SAV1))

适用

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宿主

  • 22
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克隆类型

  • 26
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多克隆

标记

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This SAV1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-210

    序列

    MLSRKKTKNE VSKPAEVQGK YVKKETSPLL RNLMPSFIRH GPTIPRRTDI CLPDSSPNAF STSGDVVSRN QSFLRTPIQR TPHEIMRRES NRLSAPSYLA RSLADVPREY GSSQSFVTEV SFAVENGDSG SRYYYSDNFF DGQRKRPLGD RAHEDYRYYE YNHDLFQRMP QNQGRHASGI GRVAATSLGN LTNHGSEDLP LPPGWSVDWT

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SAV1 (NP_068590.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:4000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SAV1 (Salvador Homolog 1 (SAV1))

    别名

    SAV1

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.,SAV1,SAV,WW45,WWP4,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Hippo Signaling Pathway,SAV1

    分子量

    44 kDa

    基因ID

    60485

    UniProt

    Q9H4B6

    途径

    Stem Cell Maintenance
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