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SART1 抗体 (AA 1-255)

This anti-SART1 antibody is a 兔 多克隆 antibody detecting SART1 in WB, IP 和 IHC. Suitable for 人.
产品编号 ABIN6147390
发货至: 中国

Quick Overview for SART1 抗体 (AA 1-255) (ABIN6147390)

抗原

See all SART1 抗体
SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

适用

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宿主

  • 30
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克隆类型

  • 33
多克隆

标记

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This SART1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-255

    序列

    MGSSKKHRGE KEAAGTTAAA GTGGATEQPP RHREHKKHKH RSGGSGGSGG ERRKRSRERG GERGSGRRGA EAEARSSTHG RERSQAEPSE RRVKREKRDD GYEAAASSKT SSGDASSLSI EETNKLRAKL GLKPLEVNAI KKEAGTKEEP VTADVINPMA LRQREELREK LAAAKEKRLL NQKLGKIKTL GEDDPWLDDT AAWIERSRQL QKEKDLAEKR AKLLEEMDQE FGVSTLVEEE FGQRRQDLYS ARDLQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SART1 (NP_005137.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:20 - 1:50

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

    别名

    SART1

    背景

    This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.,SART1,Ara1,HOMS1,SART1259,SNRNP110,Snu66,HAF,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,SART1

    分子量

    90 kDa

    基因ID

    9092

    UniProt

    O43290

    途径

    Ribonucleoprotein Complex Subunit Organization
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