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SART1 抗体 (Internal Region)

SART1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855616
发货至: 中国
  • 抗原 See all SART1 抗体
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 32
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 29
    • 2
    • 1
    克隆类型
    • 32
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART1 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
    SART1 antibody [N2C1], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human SART1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product SART1 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*
    说明

    Conjugation Note: MH

    Positive Control: Jurkat , Raji , K562 , THP-1 , HL-60 , NCI-H929 , NIH-3T3 , JC , BCL-1

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.76 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    别名
    SART1 (SART1 产品)
    别名
    Dmel\\CG6686 antibody, SART1 antibody, MGC53679 antibody, MGC132129 antibody, zgc:91927 antibody, Ara1 antibody, HOMS1 antibody, SART1259 antibody, SNRNP110 antibody, Snu66 antibody, U5-110K antibody, CG6686 gene product from transcript CG6686-RB antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antibody, squamous-cell carcinoma T-cell-recognized antigen antibody, squamous cell carcinoma antigen recognized by T cells 1 antibody, CG6686 antibody, sart1.S antibody, sart1 antibody, SART1 antibody, Sart1 antibody
    背景
    This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

    Cellular Localization: Nucleus
    分子量
    90 kDa
    基因ID
    9092
    途径
    Ribonucleoprotein Complex Subunit Organization
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