Rubicon 抗体 (AA 1-200)
Our Local Distributor
北京 101111
Quick Overview for Rubicon 抗体 (AA 1-200) (ABIN6147300)
抗原
See all Rubicon (KIAA0226) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-200
-
序列
- MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP RLLAQIDASM FARKHESPLL
-
交叉反应
- 小鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Rubicon (NP_055502.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Rubicon (KIAA0226) (KIAA0226)
-
别名
- RUBCN
-
背景
- The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,RUBCN,KIAA0226,RUBICON,SCAR15,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Cardiovascular,Heart,RUBCN
-
分子量
- 102 kDa/103 kDa/108 kDa
-
基因ID
- 9711
-
UniProt
- Q92622
-
途径
- Autophagy
抗原
-