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Rubicon 抗体 (AA 1-200)

This anti-Rubicon antibody is a Rabbit Polyclonal antibody detecting Rubicon in WB. Suitable for Human.
产品编号 ABIN6147300
发货至: 中国

Quick Overview for Rubicon 抗体 (AA 1-200) (ABIN6147300)

抗原

See all Rubicon (KIAA0226) 抗体
Rubicon (KIAA0226) (KIAA0226)

适用

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宿主

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克隆类型

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多克隆

标记

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This Rubicon antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-200

    序列

    MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP RLLAQIDASM FARKHESPLL

    交叉反应

    小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Rubicon (NP_055502.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Rubicon (KIAA0226) (KIAA0226)

    别名

    RUBCN

    背景

    The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,RUBCN,KIAA0226,RUBICON,SCAR15,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Cardiovascular,Heart,RUBCN

    分子量

    102 kDa/103 kDa/108 kDa

    基因ID

    9711

    UniProt

    Q92622

    途径

    Autophagy
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