RPSA/Laminin Receptor 抗体 (AA 1-295)
Quick Overview for RPSA/Laminin Receptor 抗体 (AA 1-295) (ABIN6147247)
抗原
See all RPSA/Laminin Receptor (RPSA) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-295
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                                            序列
- MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA TQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTDWS
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human 67kDa Laminin Receptor (NP_002286.2).
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                                            亚型
- IgG
 
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                                            应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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                                            说明
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                        HIGH QUALITY 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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                                            别名
- RPSA
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                                            背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.,RPSA,37LRP,67LR,ICAS,LAMBR,LAMR1,LBP,LBP/p40,LRP,LRP/LR,NEM/1CHD4,SA,lamR,p40,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,RPSA
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                                            分子量
- 32 kDa
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                                            基因ID
- 3921
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                                            UniProt
- P08865
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                                            途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
 抗原
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