RAD51C 抗体 (AA 1-135)
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北京 101111
Quick Overview for RAD51C 抗体 (AA 1-135) (ABIN6146645)
抗原
See all RAD51C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-135
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序列
- MRGKTFRFEM QRDLVSFPLS PAVRVKLVSA GFQTAEELLE VKPSELSKEV GISKAEALET LQIIRRECLT NKPRYAGTSE SHKKCTALEL LEQEHTQGFI ITFCSALDDI LGGGVPLMKT TEICGAPGVG KTQLW
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_002867.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))
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别名
- RAD51C
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背景
- This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.,RAD51C,BROVCA3,FANCO,R51H3,RAD51L2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD51C
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分子量
- 14 kDa/42 kDa
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基因ID
- 5889
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UniProt
- O43502
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途径
- DNA Damage Repair
抗原
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