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RAD51C 抗体 (AA 1-135)

This anti-RAD51C antibody is a 兔 多克隆 antibody detecting RAD51C in IF. Suitable for 人.
产品编号 ABIN6146644
发货至: 中国

Quick Overview for RAD51C 抗体 (AA 1-135) (ABIN6146644)

抗原

See all RAD51C 抗体
RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD51C antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    AA 1-135

    序列

    MRGKTFRFEM QRDLVSFPLS PAVRVKLVSA GFQTAEELLE VKPSELSKEV GISKAEALET LQIIRRECLT NKPRYAGTSE SHKKCTALEL LEQEHTQGFI ITFCSALDDI LGGGVPLMKT TEICGAPGVG KTQLW

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_002867.1).

    亚型

    IgG
  • 应用备注

    IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

    别名

    RAD51C

    背景

    This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.,RAD51C,BROVCA3,FANCO,R51H3,RAD51L2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD51C

    分子量

    14 kDa/42 kDa

    基因ID

    5889

    UniProt

    O43502

    途径

    DNA Damage Repair
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