PTPRU 抗体 (AA 1184-1433)
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北京 101111
Quick Overview for PTPRU 抗体 (AA 1184-1433) (ABIN6146476)
抗原
See all PTPRU 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1184-1433
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序列
- IALLPRNRDK NRSMDVLPPD RCLPFLISTD GDSNNYINAA LTDSYTRSAA FIVTLHPLQS TTPDFWRLVY DYGCTSIVML NQLNQSNSAW PCLQYWPEPG RQQYGLMEVE FMSGTADEDL VARVFRVQNI SRLQEGHLLV RHFQFLRWSA YRDTPDSKKA FLHLLAEVDK WQAESGDGRT IVHCLNGGGR SGTFCACATV LEMIRCHNLV DVFFAAKTLR NYKPNMVETM DQYHFCYDVA LEYLEGLESR
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1184-1433 of human PTPRU (NP_001181930.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))
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别名
- PTPRU
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背景
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.,PTPRU,FMI,PCP-2,PTP,PTP-J,PTP-PI,PTP-RO,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,R-PTP-U,hPTP-J,Signal Transduction,PTPRU
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分子量
- 160 kDa/161 kDa/162 kDa
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基因ID
- 10076
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UniProt
- Q92729
抗原
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