PTPRU 抗体 (AA 579-749)
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Quick Overview for PTPRU 抗体 (AA 579-749) (ABIN5684107)
抗原
See all PTPRU 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 579-749
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原理
- PTPRU Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PTPRU (AA: 579-749) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))
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别名
- PTPRU
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背景
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.
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分子量
- 162.4 kDa
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UniProt
- Q92729
抗原
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