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PKC gamma 抗体

This anti-PKC gamma antibody is a 兔 多克隆 antibody detecting PKC gamma in WB 和 IF. Suitable for 人.
产品编号 ABIN6146206
发货至: 中国

Quick Overview for PKC gamma 抗体 (ABIN6146206)

抗原

See all PKC gamma (PRKCG) 抗体
PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC gamma antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide of human PKC gamma

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))

    别名

    PRKCG

    背景

    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene.,PRKCG,PKC-gamma,PKCC,PKCG,SCA14,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PRKCG

    分子量

    62 kDa/78 kDa

    基因ID

    5582

    UniProt

    P05129

    途径

    WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
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