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PPARD 抗体 (AA 102-361)

This anti-PPARD antibody is a 兔 多克隆 antibody detecting PPARD in WB 和 IHC. Suitable for 人.
产品编号 ABIN6146002
发货至: 中国

Quick Overview for PPARD 抗体 (AA 102-361) (ABIN6146002)

抗原

See all PPARD 抗体
PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

适用

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宿主

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克隆类型

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多克隆

标记

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This PPARD antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 102-361

    序列

    IRMKLEYEKC ERSCKIQKKN RNKCQYCRFQ KCLALGMSHN AIRFGRMPEA EKRKLVAGLT ANEGSQYNPQ VADLKAFSKH IYNAYLKNFN MTKKKARSIL TGKASHTAPF VIHDIETLWQ AEKGLVWKQL VNGLPPYKEI SVHVFYRCQC TTVETVRELT EFAKSIPSFS SLFLNDQVTL LKYGVHEAIF AMLASIVNKD GLLVANGSGF VTREFLRSLR KPFSDIIEPK FEFAVKFNAL ELDDSDLALF IAAIILCGGE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 102-361 of human PPARD (NP_803184.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

    别名

    PPARD

    背景

    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.,PPARD,FAAR,NR1C2,NUC1,NUCI,NUCII,PPARB,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Cardiovascular,Heart,Cardiac metabolism,PPARD

    分子量

    38 kDa/40 kDa/45 kDa/49 kDa

    基因ID

    5467

    UniProt

    Q03181

    途径

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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