PLOD2 抗体 (AA 470-650)
Quick Overview for PLOD2 抗体 (AA 470-650) (ABIN6145788)
抗原
See all PLOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-650
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序列
- KTLRSEMNER NYFVRDKLDP DMALCRNARE MTLQREKDSP TPETFQMLSP PKGVFMYISN RHEFGRLLST ANYNTSHYNN DLWQIFENPV DWKEKYINRD YSKIFTENIV EQPCPDVFWF PIFSEKACDE LVEEMEHYGK WSGGKHHDSR ISGGYENVPT DDIHMKQVDL ENVWLHFIRE F
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 470-650 of human PLOD2 (NP_891988.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
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别名
- PLOD2
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背景
- The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.,PLOD2,BRKS2,LH2,TLH,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,PLOD2
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分子量
- 49 kDa/84 kDa/87 kDa
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基因ID
- 5352
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UniProt
- O00469
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途径
- SARS-CoV-2 Protein Interactome
抗原
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