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PLOD2 抗体 (Middle Region)

PLOD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775556
发货至: 中国
  • 抗原 See all PLOD2 抗体
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 22
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 兔
    宿主
    • 17
    • 6
    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    This PLOD2 antibody is un-conjugated
    应用范围
    • 18
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    IKGKTLRSEM NERNYFVRDK LDPDMALCRN AREMTLQREK DSPTPETFQM
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PLOD2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PLOD2
    Top Product
    Discover our top product PLOD2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 758 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    别名
    PLOD2 (PLOD2 产品)
    别名
    D530025C14Rik antibody, LH2 antibody, Plod-2 antibody, TLH antibody, procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 antibody, Plod2 antibody, PLOD2 antibody
    背景
    PLOD2 forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: LH2, TLH
    Protein Interaction Partner: ITGB1BP2, SUPT5H, CSDE1, SF1, UGP2, TPP2, VASN, RNF123, NUSAP1, SAMHD1, DNPEP, GANAB, SWAP70, XPO7, PACSIN2, FAF1, HSPH1, SEC23A, PRMT3, FARSB, USP15, RANBP3, SET, RPL24, PTPN12, NCL, NARS, JUP, GART, XRCC6, AP2B1, gag-pol, UBL4A, OS9, FBXO6, UBC, VHL, Fa
    Protein Size: 758
    分子量
    84 kDa
    基因ID
    5352
    NCBI登录号
    NM_182943, NP_891988
    途径
    SARS-CoV-2 Protein Interactome
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