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MCAM 抗体

MCAM 适用: 人 FACS, WB, IHC (p), IP, IHC (fro) 宿主: 小鼠 Monoclonal P1H12 unconjugated
产品编号 ABIN614548
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MCAM antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes Human CD146 also known as MUC18. The antibody P1H12 has been reported to cross-react with Mouse, Rabbit, Canine, but not Rat.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    Immunization of mice with HUVEC
    克隆位点
    P1H12
    亚型
    IgG1
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2 containing ≤ 0.09 % Sodium Azide, BSA and/or Gelatin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    CD146 (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景
    Human CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50 % of the mass from carbohydrates.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
    基因ID
    4162
    NCBI登录号
    NP_006491
    UniProt
    P43121
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