MCAM 抗体
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北京 101111
Quick Overview for MCAM 抗体 (ABIN614548)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Human CD146 also known as MUC18. The antibody P1H12 has been reported to cross-react with Mouse, Rabbit, Canine, but not Rat.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography
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免疫原
- Immunization of mice with HUVEC
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2 containing ≤ 0.09 % Sodium Azide, BSA and/or Gelatin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- Human CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50 % of the mass from carbohydrates.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
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基因ID
- 4162
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NCBI登录号
- NP_006491
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UniProt
- P43121
抗原
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