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MCAM 抗体

This anti-MCAM antibody is a 小鼠 单克隆 antibody detecting MCAM in FACS, WB, IP, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN614548
发货至: 中国

Quick Overview for MCAM 抗体 (ABIN614548)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

P1H12
  • 特异性

    Recognizes Human CD146 also known as MUC18. The antibody P1H12 has been reported to cross-react with Mouse, Rabbit, Canine, but not Rat.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography

    免疫原

    Immunization of mice with HUVEC

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2 containing ≤ 0.09 % Sodium Azide, BSA and/or Gelatin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    CD146

    背景

    Human CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50 % of the mass from carbohydrates.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen

    基因ID

    4162

    NCBI登录号

    NP_006491

    UniProt

    P43121
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