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GDF15 抗体 (AA 40-243)

This anti-GDF15 antibody is a 兔 多克隆 antibody detecting GDF15 in WB. Suitable for 人.
产品编号 ABIN6145370
发货至: 中国

Quick Overview for GDF15 抗体 (AA 40-243) (ABIN6145370)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 116
  • 41
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宿主

  • 106
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克隆类型

  • 103
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多克隆

标记

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This GDF15 antibody is un-conjugated

应用范围

  • 112
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Western Blotting (WB)
  • 抗原表位

    • 15
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    AA 40-243

    序列

    EGPALRRSYW RHLRRLVLGP PEPPFSHVCQ VGDPVLRGVA APVERAQLGG PELQRLTQRL VQVMRRRRCV GLSAPQLGVP RQVLALELPE ALCRECPPRQ RALRQMEPFP LRVFVNPSLR VLDSRLVTFP EGCESVAGFL ACVPRFQAVQ ISGLDPNGEQ VVWQASGWAA RIIQHEMDHL QGCLFIDKMD SRTFTNVYWM KVND

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 40-243 of human PDF (NP_071736.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    PDF

    背景

    Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.,PDF,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Amino acid metabolism,Nucleotide metabolism,PDF

    分子量

    27 kDa

    基因ID

    64146

    UniProt

    Q9HBH1

    途径

    SARS-CoV-2 Protein Interactome
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