GDF15 抗体 (AA 40-243)
Quick Overview for GDF15 抗体 (AA 40-243) (ABIN6145370)
抗原
See all GDF15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-243
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序列
- EGPALRRSYW RHLRRLVLGP PEPPFSHVCQ VGDPVLRGVA APVERAQLGG PELQRLTQRL VQVMRRRRCV GLSAPQLGVP RQVLALELPE ALCRECPPRQ RALRQMEPFP LRVFVNPSLR VLDSRLVTFP EGCESVAGFL ACVPRFQAVQ ISGLDPNGEQ VVWQASGWAA RIIQHEMDHL QGCLFIDKMD SRTFTNVYWM KVND
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-243 of human PDF (NP_071736.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
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背景
- Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.,PDF,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Amino acid metabolism,Nucleotide metabolism,PDF
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分子量
- 27 kDa
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基因ID
- 64146
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UniProt
- Q9HBH1
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途径
- SARS-CoV-2 Protein Interactome
抗原
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