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PATZ1 抗体 (AA 250-350)

This anti-PATZ1 antibody is a 兔 多克隆 antibody detecting PATZ1 in WB. Suitable for 人.
产品编号 ABIN6145252
发货至: 中国

Quick Overview for PATZ1 抗体 (AA 250-350) (ABIN6145252)

抗原

See all PATZ1 (ZNF278) 抗体
PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

适用

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宿主

  • 19
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克隆类型

  • 21
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多克隆

标记

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This PATZ1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 250-350

    序列

    PFPSVASSAP PLTGKRGRGR PRKANLLDSM FGSPGGLREA GILPCGLCGK VFTDANRLRQ HEAQHGVTSL QLGYIDLPPP RLGENGLPIS EDPDGPRKRS R

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human PATZ1 (NP_114440.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:4000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

    别名

    PATZ1

    背景

    The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.,PATZ1,MAZR,PATZ,RIAZ,ZBTB19,ZNF278,ZSG,dJ400N23,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,PATZ1

    分子量

    57 kDa/69 kDa/74 kDa

    基因ID

    23598

    UniProt

    Q9HBE1
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