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PABPN1 抗体 (AA 1-100)

This anti-PABPN1 antibody is a 兔 多克隆 antibody detecting PABPN1 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6145153
发货至: 中国

Quick Overview for PABPN1 抗体 (AA 1-100) (ABIN6145153)

抗原

See all PABPN1 抗体
PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

适用

  • 30
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  • 1

宿主

  • 30

克隆类型

  • 18
  • 12
多克隆

标记

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This PABPN1 antibody is un-conjugated

应用范围

  • 22
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    AA 1-100

    序列

    MAAAAAAAAA AGAAGGRGSG PGRRRHLVPG AGGEAGEGAP GGAGDYGNGL ESEELEPEEL LLEPEPEPEP EEEPPRPRAP PGAPGPGPGS GAPGSQEEEE

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

  • 抗原

    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

    别名

    PABPN1

    背景

    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2,Epigenetics & Nuclear Signaling,RNA Binding,PABPN1

    分子量

    31 kDa/32 kDa/37 kDa

    基因ID

    8106

    UniProt

    Q86U42
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