OAZ1 抗体 (AA 1-68)
Quick Overview for OAZ1 抗体 (AA 1-68) (ABIN6144987)
抗原
See all OAZ1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-68
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序列
- MVKSSLQRIL NSHCFAREKE GDKPSATIHA SRTMPLLSLH SRGGSSSESS RVSLHCCSNP GPGPRWCS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human OAZ1 (NP_004143.1).
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亚型
- IgG
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anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibody
OAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 120-132) antibodyVerified OAZ1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 2-31), (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB18521 unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
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别名
- OAZ1
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背景
- The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.,OAZ1,AZ1,AZI,OAZ,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Endocrine & Metabolism,Amino acid metabolism,OAZ1
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分子量
- 25 kDa
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基因ID
- 4946
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UniProt
- P54368
抗原
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