MSH3 抗体 (AA 617-761)
Quick Overview for MSH3 抗体 (AA 617-761) (ABIN6144059)
抗原
See all MSH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 617-761
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序列
- FNTSEEHHAD MYRSDLPNPD TLSAELHCWR IKWKHRGKDI ELPSTIYEAL HLPDIKFFPN VYALLKVLCI LPVMKVENER YENGRKRLKA YLRNTLTDQR SSNLALLNIN FDIKHDLDLM VDTYIKLYTS KSELPTDNSE TVENT
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3 (NP_004696.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MSH3 (MutS Homolog 3 (MSH3))
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别名
- MSH3
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背景
- The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.,MSH3,DUP,FAP4,MRP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MSH3
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分子量
- 127 kDa
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基因ID
- 4437
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UniProt
- P20585
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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