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MME 抗体 (AA 52-352)

This anti-MME antibody is a 兔 多克隆 antibody detecting MME in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6143900
发货至: 中国

Quick Overview for MME 抗体 (AA 52-352) (ABIN6143900)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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宿主

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克隆类型

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多克隆

标记

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This MME antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 52-352

    序列

    YDDGICKSSD CIKSAARLIQ NMDATTEPCT DFFKYACGGW LKRNVIPETS SRYGNFDILR DELEVVLKDV LQEPKTEDIV AVQKAKALYR SCINESAIDS RGGEPLLKLL PDIYGWPVAT ENWEQKYGAS WTAEKAIAQL NSKYGKKVLI NLFVGTDDKN SVNHVIHIDQ PRLGLPSRDY YECTGIYKEA CTAYVDFMIS VARLIRQEER LPIDENQLAL EMNKVMELEK EIANATAKPE DRNDPMLLYN KMTLAQIQNN FSLEINGKPF SWLNFTNEIM STVNISITNE EDVVVYAPEY L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 52-352 of human CD10/CD10/MME (NP_009220.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wu, Kong, Wang, Chen, Wang: "Spatiotemporal expression of endogenous opioid processing enzymes in mouse uterus at peri-implantation." in: Cell and tissue research, Vol. 363, Issue 2, pp. 555-65, (2016) (PubMed).

  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    MME

    背景

    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.,CALLA,CD10,CMT2T,NEP,SCA43,SFE,MME,Cancer,Tumor immunology,Immunology & Inflammation,CD markers,Neuroscience,Neurodegenerative Diseases,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,MME

    分子量

    85 kDa

    基因ID

    4311

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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