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MLH3 抗体 (AA 1180-1429)

This anti-MLH3 antibody is a 兔 多克隆 antibody detecting MLH3 in WB. Suitable for 人.
产品编号 ABIN6143878
发货至: 中国

Quick Overview for MLH3 抗体 (AA 1180-1429) (ABIN6143878)

抗原

See all MLH3 抗体
MLH3 (MutL Homolog 3 (MLH3))

适用

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宿主

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克隆类型

  • 16
多克隆

标记

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This MLH3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1180-1429

    序列

    RFTKGMIHSM QVLQQVDNKF IACLMSTKTE ENGEADSYEK QQAQGSGRKK LLSSTLIPPL EITVTEEQRR LLWCYHKNLE DLGLEFVFPD TSDSLVLVGK VPLCFVEREA NELRRGRSTV TKSIVEEFIR EQLELLQTTG GIQGTLPLTV QKVLASQACH GAIKFNDGLS LQESCRLIEA LSSCQLPFQC AHGRPSMLPL ADIDHLEQEK QIKPNLTKLR KMAQAWRLFG KAECDTRQSL QQSMPPCEPP

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1180-1429 of human MLH3 (NP_055196.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MLH3 (MutL Homolog 3 (MLH3))

    别名

    MLH3

    背景

    This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.,MLH3,HNPCC7,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MLH3

    分子量

    161 kDa/163 kDa

    基因ID

    27030

    UniProt

    Q9UHC1

    途径

    Chromatin Binding
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