MFN2 抗体 (AA 687-757)
Quick Overview for MFN2 抗体 (AA 687-757) (ABIN6143801)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 687-757
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序列
- QVQQELSGTF AHLCQQVDIT RDNLEQEIAA MNKKVEALDS LQSRAKLLRN KAGWLDSELN MFTHQYLQPS R
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- MFN2
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背景
- This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.,MFN2,CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,HMSN6A,HSG,MARF,mitofusin-2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Mitochondrial Control of Autophagy,MFN2
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分子量
- 68 kDa/86 kDa
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基因ID
- 170731
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途径
- Skeletal Muscle Fiber Development
抗原
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