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METAP2 抗体 (AA 1-220)

This anti-METAP2 antibody is a 兔 多克隆 antibody detecting METAP2 in WB. Suitable for 人.
产品编号 ABIN6143752
发货至: 中国

Quick Overview for METAP2 抗体 (AA 1-220) (ABIN6143752)

抗原

See all METAP2 抗体
METAP2 (Methionyl Aminopeptidase 2 (METAP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This METAP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-220

    序列

    MAGVEEVAAS GSHLNGDLDP DDREEGAAST AEEAAKKKRR KKKKSKGPSA AGEQEPDKES GASVDEVARQ LERSALEDKE RDEDDEDGDG DGDGATGKKK KKKKKKRGPK VQTDPPSVPI CDLYPNGVFP KGQECEYPPT QDGRTAAWRT TSEEKKALDQ ASEEIWNDFR EAAEAHRQVR KYVMSWIKPG MTMIEICEKL EDCSRKLIKE NGLNAGLAFP

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human METAP2 (NP_006829.1).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    METAP2 (Methionyl Aminopeptidase 2 (METAP2))

    别名

    METAP2

    背景

    The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.,METAP2,MAP2,MNPEP,p67eIF2,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,METAP2

    分子量

    50 kDa/52 kDa

    基因ID

    10988

    UniProt

    P50579

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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