MEPCE 抗体 (AA 470-689)
Quick Overview for MEPCE 抗体 (AA 470-689) (ABIN6143737)
抗原
See all MEPCE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-689
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序列
- MVGLDIDSRL IHSARQNIRH YLSEELRLPP QTLEGDPGAE GEEGTTTVRK RSCFPASLTA SRGPIAAPQV PLDGADTSVF PNNVVFVTGN YVLDRDDLVE AQTPEYDVVL CLSLTKWVHL NWGDEGLKRM FRRIYRHLRP GGILVLEPQP WSSYGKRKTL TETIYKNYYR IQLKPEQFSS YLTSPDVGFS SYELVATPHN TSKGFQRPVY LFHKARSPSH
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 470-689 of human MEPCE (NP_062552.2).
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亚型
- IgG
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anti-Methylphosphate Capping Enzyme (MEPCE) (Internal Region) antibody
Verified MEPCE 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Methylphosphate Capping Enzyme (MEPCE) (AA 263-312) antibodyMEPCE 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Methylphosphate Capping Enzyme (MEPCE) antibodyMEPCE 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MEPCE (Methylphosphate Capping Enzyme (MEPCE))
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别名
- MEPCE
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背景
- S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA, leading to stabilize it. Also has a non-enzymatic function as part of the 7SK RNP complex: the 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC. In the 7SK RNP complex, MEPCE is required to stabilize 7SK RNA and facilitate the assembly of 7SK RNP complex. MEPCE has a non-enzymatic function in the 7SK RNP complex, interaction with LARP7 within the 7SK RNP complex occluding its catalytic center.,MEPCE,BCDIN3,Epigenetics & Nuclear Signaling,RNA Binding,MEPCE
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分子量
- 24 kDa/74 kDa
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基因ID
- 56257
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UniProt
- Q7L2J0
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途径
- Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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