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MECOM 抗体 (AA 1-120)

This anti-MECOM antibody is a 兔 多克隆 antibody detecting MECOM in WB. Suitable for 人.
产品编号 ABIN6143677
发货至: 中国

Quick Overview for MECOM 抗体 (AA 1-120) (ABIN6143677)

抗原

See all MECOM 抗体
MECOM (MDS1 and EVI1 Complex Locus (MECOM))

适用

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宿主

  • 45
  • 14
  • 1

克隆类型

  • 48
  • 12
多克隆

标记

  • 35
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This MECOM antibody is un-conjugated

应用范围

  • 44
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Western Blotting (WB)
  • 抗原表位

    • 12
    • 9
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    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1-120

    序列

    MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA TSSEAFTPKE GSPYKAPIYI PDDIPIPAEF ELRESNMPGA GLGIWTKRKI EVGEKFGPYV GEQRSNLKDP

    交叉反应

    小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MECOM (NP_004982.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MECOM (MDS1 and EVI1 Complex Locus (MECOM))

    别名

    MECOM

    背景

    The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.,MECOM,AML1-EVI-1,EVI1,KMT8E,MDS1,MDS1-EVI1,PRDM3,RUSAT2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,MECOM

    分子量

    18 kDa/117 kDa/118 kDa/125 kDa/139 kDa

    基因ID

    2122

    UniProt

    Q03112, Q13465
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