MANF 抗体 (AA 25-182)
Quick Overview for MANF 抗体 (AA 25-182) (ABIN6143461)
抗原
See all MANF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-182
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序列
- SRALRPGDCE VCISYLGRFY QDLKDRDVTF SPATIENELI KFCREARGKE NRLCYYIGAT DDAATKIINE VSKPLAHHIP VEKICEKLKK KDSQICELKY DKQIDLSTVD LKKLRVKELK KILDDWGETC KGCAEKSDYI RKINELMPKY APKAASAR
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human ARMET/ARP/MANF (NP_006001.4).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
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别名
- MANF
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背景
- The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.,MANF,ARMET,ARP,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,Neuroscience,MANF
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分子量
- 20 kDa
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基因ID
- 7873
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UniProt
- P55145
抗原
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