LIN28A 抗体 (AA 142-209)
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北京 101111
Quick Overview for LIN28A 抗体 (AA 142-209) (ABIN6143238)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 142-209
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序列
- CGGLDHHAKE CKLPPQPKKC HFCQSISHMV ASCPLKAQQG PSAQGKPTYF REEEEEIHSP TLLPEAQN
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 142-209 of human LIN28 (NP_078950.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- LIN28A
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背景
- This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.,LIN28A,CSDD1,LIN-28,LIN28,ZCCHC1,lin-28A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,Embryonic Stem Cells,LIN28A
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分子量
- 22 kDa
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基因ID
- 79727
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UniProt
- Q9H9Z2
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途径
- Stem Cell Maintenance
抗原
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