LAMB2 抗体 (AA 1579-1798)
Quick Overview for LAMB2 抗体 (AA 1579-1798) (ABIN6143070)
抗原
See all LAMB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1579-1798
-
序列
- DVRRAEQLLQ DARRARSWAE DEKQKAETVQ AALEEAQRAQ GIAQGAIRGA VADTRDTEQT LYQVQERMAG AERALSSAGE RARQLDALLE ALKLKRAGNS LAASTAEETA GSAQGRAQEA EQLLRGPLGD QYQTVKALAE RKAQGVLAAQ ARAEQLRDEA RDLLQAAQDK LQRLQELEGT YEENERALES KAAQLDGLEA RMRSVLQAIN LQVQIYNTCQ
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1579-1798 of human LAMB2 (NP_002283.3).
-
亚型
- IgG
-
-
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 1498-1716) antibody
LAMB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 939-1129) antibodyLAMB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 1176-1309) antibodyLAMB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (N-Term) antibodyLAMB2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 75-223) antibodyLAMB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 1579-1606), (C-Term) antibodyLAMB2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20568 unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) antibodyLAMB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 38-350) antibodyLAMB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) (AA 1178-1311) antibodyLAMB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 2 (Laminin S) (LAMB2) antibodyLAMB2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
-
别名
- LAMB2
-
背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma . Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form.,LAMB2,LAMS,NPHS5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Neuroscience,Cardiovascular,Angiogenesis,LAMB2
-
分子量
- 195 kDa
-
基因ID
- 3913
-
UniProt
- P55268
-
途径
- Skeletal Muscle Fiber Development
抗原
-
