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KLHL3 抗体 (AA 1-110)

This 兔 多克隆 antibody specifically detects KLHL3 in WB. It exhibits reactivity toward 人.
产品编号 ABIN6142937
发货至: 中国
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Quick Overview for KLHL3 抗体 (AA 1-110) (ABIN6142937)

抗原

See all KLHL3 抗体
KLHL3 (Kelch-Like 3 (KLHL3))

适用

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宿主

  • 50
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克隆类型

  • 52
多克隆

标记

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This KLHL3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-110

    序列

    MEGESVKLSS QTLIQAGDDE KNQRTITVNP AHMGKAFKVM NELRSKQLLC DVMIVAEDVE IEAHRVVLAA CSPYFCAMFT GDMSESKAKK IEIKDVDGQT LSKLIDYIYT

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human KLHL3 (NP_059111.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KLHL3 (Kelch-Like 3 (KLHL3))

    别名

    KLHL3

    背景

    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,KLHL3,PHA2D,Cell Biology & Developmental Biology,KLHL3

    分子量

    55 kDa/61 kDa/64 kDa

    基因ID

    26249

    UniProt

    Q9UH77
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