电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IRF3 抗体 (AA 1-260)

This anti-IRF3 antibody is a 兔 多克隆 antibody detecting IRF3 in WB, IHC, IF 和 ChIP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6142528
发货至: 中国

Quick Overview for IRF3 抗体 (AA 1-260) (ABIN6142528)

抗原

See all IRF3 抗体
IRF3 (Interferon Regulatory Factor 3 (IRF3))

适用

  • 145
  • 92
  • 60
  • 31
  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 145
  • 23
  • 2

克隆类型

  • 127
  • 43
多克隆

标记

  • 105
  • 9
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This IRF3 antibody is un-conjugated

应用范围

  • 134
  • 71
  • 47
  • 42
  • 29
  • 27
  • 25
  • 21
  • 21
  • 19
  • 6
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

    • 16
    • 15
    • 15
    • 13
    • 10
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260

    序列

    MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:20 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." in: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).

  • 抗原

    IRF3 (Interferon Regulatory Factor 3 (IRF3))

    别名

    IRF3

    背景

    This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,IIAE7,IRF3,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF3

    分子量

    12 kDa/16 kDa/33 kDa/47 kDa/49 kDa

    基因ID

    3661

    UniProt

    Q14653

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
You are here:
Chat with us!