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INCENP 抗体 (AA 785-914)

This 兔 多克隆 anti-INCENP antibody specifically detects INCENP in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6142441
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for INCENP 抗体 (AA 785-914) (ABIN6142441)

抗原

See all INCENP 抗体
INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

适用

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宿主

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克隆类型

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多克隆

标记

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This INCENP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 785-914

    序列

    ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_064623.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

    别名

    INCENP

    背景

    In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008],INCENP,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,INCENP

    分子量

    104 kDa/105 kDa

    基因ID

    3619

    UniProt

    Q9NQS7

    途径

    Cell Division Cycle
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