INCENP 抗体 (AA 785-914)
Quick Overview for INCENP 抗体 (AA 785-914) (ABIN6142441)
抗原
See all INCENP 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 785-914
- 
                                            序列
- ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH
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                                            交叉反应
- 人, 大鼠
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                                            产品特性
- Polyclonal Antibodies
- 
                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_064623.2).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000
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                                            说明
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                        HIGH QUALITY 
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
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                                            别名
- INCENP
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                                            背景
- In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008],INCENP,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,INCENP
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                                            分子量
- 104 kDa/105 kDa
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                                            基因ID
- 3619
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                                            UniProt
- Q9NQS7
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                                            途径
- Cell Division Cycle
 抗原
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