Serotonin Receptor 2B 抗体 (AA 382-481)
Quick Overview for Serotonin Receptor 2B 抗体 (AA 382-481) (ABIN6142069)
抗原
See all Serotonin Receptor 2B (HTR2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 382-481
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序列
- LFNKTFRDAF GRYITCNYRA TKSVKTLRKR SSKIYFRNPM AENSKFFKKH GIRNGINPAM YQSPMRLRSS TIQSSSIILL DTLLLTENEG DKTEEQVSYV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP_000858.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:10 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Serotonin Receptor 2B (HTR2B)
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别名
- HTR2B
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背景
- This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.,HTR2B,5-HT(2B),5-HT-2B,5-HT2B,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,HTR2B
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分子量
- 54 kDa
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基因ID
- 3357
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UniProt
- P41595
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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