HDAC5 抗体 (AA 350-450)
Quick Overview for HDAC5 抗体 (AA 350-450) (ABIN6141677)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 350-450
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序列
 - RALPLDSSPN QFSLYTSPSL PNISLGLQAT VTVTNSHLTA SPKLSTQQEA ERQALQSLRQ GGTLTGKFMS TSSIPGCLLG VALEGDGSPH GHASLLQHVL L
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交叉反应
 - 人
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产品特性
 - Polyclonal Antibodies
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纯化方法
 - Affinity purification
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免疫原
 - A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HDAC5 (NP_005465.2).
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亚型
 - IgG
 
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应用备注
 - WB,1:500 - 1:2000,IF,1:20 - 1:50
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说明
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HIGH QUALITY
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
 - HDAC5
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背景
 - Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.,HDAC5,HD5,NY-CO-9,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC5
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分子量
 - 112 kDa/121 kDa/122 kDa
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基因ID
 - 10014
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UniProt
 - Q9UQL6
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途径
 - Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
 
抗原
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