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HDAC5 抗体 (AA 550-650)

This anti-HDAC5 antibody is a 兔 多克隆 antibody detecting HDAC5 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN6141675
发货至: 中国

Quick Overview for HDAC5 抗体 (AA 550-650) (ABIN6141675)

抗原

See all HDAC5 抗体
HDAC5 (Histone Deacetylase 5 (HDAC5))

适用

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宿主

  • 83
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克隆类型

  • 83
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多克隆

标记

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This HDAC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 550-650

    序列

    EETEEELTEQ QEVLLGEGAL TMPREGSTES ESTQEDLEEE DEEDDGEEEE DCIQVKDEEG ESGAEEGPDL EEPGAGYKKL FSDAQPLQPL QVYQAPLSLA T

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 550-650 of human HDAC5 (NP_005465.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HDAC5 (Histone Deacetylase 5 (HDAC5))

    别名

    HDAC5

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.,HDAC5,HD5,NY-CO-9,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC5

    分子量

    112 kDa/121 kDa/122 kDa

    基因ID

    10014

    UniProt

    Q9UQL6

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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