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HDAC4 抗体 (AA 451-650)

This anti-HDAC4 antibody is a 兔 多克隆 antibody detecting HDAC4 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN6141669
发货至: 中国

Quick Overview for HDAC4 抗体 (AA 451-650) (ABIN6141669)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

  • 120
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  • 1
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宿主

  • 109
  • 15
  • 1

克隆类型

  • 106
  • 19
多克隆

标记

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This HDAC4 antibody is un-conjugated

应用范围

  • 86
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  • 11
  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-650

    序列

    PSIHKLRQHR PLGRTQSAPL PQNAQALQHL VIQQQHQQFL EKHKQQFQQQ QLQMNKIIPK PSEPARQPES HPEETEEELR EHQALLDEPY LDRLPGQKEA HAQAGVQVKQ EPIESDEEEA EPPREVEPGQ RQPSEQELLF RQQALLLEQQ RIHQLRNYQA SMEAAGIPVS FGGHRPLSRA QSSPASATFP VSVQEPPTKP

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 451-650 of human HDAC4 (NP_006028.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:100 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.,HDAC4,AHO3,BDMR,HA6116,HD4,HDAC-4,HDAC-A,HDACA,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC4

    分子量

    106 kDa/119 kDa

    基因ID

    9759

    UniProt

    P56524

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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