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Granulin 抗体 (AA 281-336)

GRN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141429
发货至: 中国
  • 抗原 See all Granulin (GRN) 抗体
    Granulin (GRN)
    抗原表位
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-336
    适用
    • 50
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 9
    • 5
    • 2
    • 1
    克隆类型
    • 46
    • 12
    多克隆
    标记
    • 35
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Granulin antibody is un-conjugated
    应用范围
    • 51
    • 19
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).
    亚型
    IgG
    Top Product
    Discover our top product GRN Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Granulin (GRN)
    别名
    GRN (GRN 产品)
    背景
    Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN
    分子量
    44 kDa/46 kDa/63 kDa
    基因ID
    2896
    UniProt
    P28799
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