Granulin 抗体 (AA 281-336)
Quick Overview for Granulin 抗体 (AA 281-336) (ABIN6141429)
抗原
See all Granulin (GRN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 281-336
-
序列
- DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).
-
亚型
- IgG
-
-
anti-Granulin (GRN) (AA 361-585) antibody
GRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 31-269) antibodyGRN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (Center) antibodyGRN 适用: 人, 小鼠, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) antibodyGRN 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Granulin (GRN) (AA 451-550) antibodyGRN 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 44-255) antibodyGRN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Granulin (GRN) (AA 20-310) antibodyGRN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Granulin (GRN) (AA 21-120) antibodyGRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Granulin (GRN)
-
别名
- GRN
-
背景
- Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN
-
分子量
- 44 kDa/46 kDa/63 kDa
-
基因ID
- 2896
-
UniProt
- P28799
抗原
-
