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GREM1 抗体 (AA 44-143)

The 兔 多克隆 anti-GREM1 antibody is suitable to detect GREM1 in samples from 人. It has been validated for WB.
产品编号 ABIN6141382
发货至: 中国
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Quick Overview for GREM1 抗体 (AA 44-143) (ABIN6141382)

抗原

See all GREM1 抗体
GREM1 (Gremlin 1 (GREM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GREM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 44-143

    序列

    ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 44-143 of human GREM1 (NP_001178252.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GREM1 (Gremlin 1 (GREM1))

    别名

    GREM1

    背景

    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GREM1,C15DUPq,CKTSF1B1,CRAC1,CRCS4,DAND2,DRM,DUP15q,GREMLIN,HMPS,HMPS1,IHG-2,MPSH,PIG2,gremlin-1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Immunology & Inflammation,Cytokines,Stem Cells,Embryonic Stem Cells,GREM1

    分子量

    16 kDa/20 kDa

    基因ID

    26585

    UniProt

    O60565

    途径

    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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