Mesothelin 抗体 (AA 1-70)
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北京 101111
Quick Overview for Mesothelin 抗体 (AA 1-70) (ABIN6141320)
抗原
See all Mesothelin (MSLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-70
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序列
- MDVTSQARGV GLEMYPGTAQ PAAPNTTSPE LNLSHPLLGT ALANGTGELS EHQQYVIGLF LSCLYTIFLF
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human GPER1 (NP_001496.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Mesothelin (MSLN)
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别名
- GPER1
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背景
- This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.,GPER1,CEPR,CMKRL2,DRY12,FEG-1,GPCR-Br,GPER,GPR30,LERGU,LERGU2,LyGPR,mER,GPER1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GPER1
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分子量
- 42 kDa
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基因ID
- 2852
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UniProt
- Q99527
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途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
抗原
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