GEN1 抗体 (AA 669-908)
This anti-GEN1 antibody is a 兔 多克隆 antibody detecting GEN1 in WB. Suitable for 人.
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Quick Overview for GEN1 抗体 (AA 669-908) (ABIN6141058)
抗原
See all GEN1 抗体
GEN1
(Gen Endonuclease Homolog 1 (GEN1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This GEN1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 669-908
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序列
- LQDLPLKERI FTKLSYPQDN LQPDVNLKTL SILSVKESCI ANSGSDCTSH LSKDLPGIPL QNESRDSKIL KGDQLLQEDY KVNTSVPYSV SNTVVKTCNV RPPNTALDHS RKVDMQTTRK ILMKKSVCLD RHSSDEQSAP VFGKAKYTTQ RMKHSSQKHN SSHFKESGHN KLSSPKIHIK ETEQCVRSYE TAENEESCFP DSTKSSLSSL QCHKKENNSG TCLDSPLPLR QRLKLRFQST
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 669-908 of human GEN1 (NP_872431.3).
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亚型
- IgG
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anti-Gen Endonuclease Homolog 1 (GEN1) (AA 60-89), (N-Term) antibody
GEN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB23975 unconjugated
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GEN1 (Gen Endonuclease Homolog 1 (GEN1))
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别名
- GEN1
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背景
- This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.,GEN1,Gen,Epigenetics & Nuclear Signaling,DNA Damage & Repair,GEN1
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分子量
- 102 kDa
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基因ID
- 348654
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UniProt
- Q17RS7
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途径
- DNA Damage Repair
抗原
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