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GCLC 抗体 (AA 1-252)

Cited in 1 publication. This 兔 多克隆 anti-GCLC antibody specifically detects GCLC in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6141016
发货至: 中国
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Quick Overview for GCLC 抗体 (AA 1-252) (ABIN6141016)

抗原

See all GCLC 抗体
GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

适用

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宿主

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克隆类型

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多克隆

标记

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This GCLC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
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    AA 1-252

    序列

    MGLLSQGSPL SWEETKRHAD HVRRHGILQF LHIYHAVKDR HKDVLKWGDE VEYMLVSFDH ENKKVRLVLS GEKVLETLQE KGERTNPNHP TLWRPEYGSY MIEGTPGQPY GGTMSEFNTV EANMRKRRKE ATSILEENQA LCTITSFPRL GCPGFTLPEV KPNPVEGGAS KSLFFPDEAI NKHPRFSTLT RNIRHRRGEK VVINVPIFKD KNTPSPFIET FTEDDEASRA SKPDHIYMDA MGFGMGNCCL QV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human GCLC (NP_001489.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:3000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Khaliq, Jing, Ke, Ke-Li, Peng-Peng, Cui, Wei-Wei, Zhixin, Hua-Zhen, Hui, Ju-Ming, Ke-Mei: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).

  • 抗原

    GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

    别名

    GCLC

    背景

    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.,GCLC,GCL,GCS,GLCL,GLCLC,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,GCLC

    分子量

    72 kDa

    基因ID

    2729

    UniProt

    P48506

    途径

    Cell RedoxHomeostasis
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