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FURIN 抗体 (AA 120-370)

Name: FURIN 抗体 (AA 120-370)
Brand: antibodies-online
SKU: ABIN6140815
Availability: OutOfStock

This 兔多克隆 anti-FURIN antibody specifically detects FURIN in WB, IHC, IP 和 IF. The antibody is reactive with 人 samples.

Western blot analysis of extracts of HeLa cells, using Furin antibody (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322) at 1:1000 dilution. (FURIN 抗体 (AA 120-370))

Immunofluorescence analysis of U-2 OS cells using Furin Rabbit pAb (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322) at dilution of 1:150 (40x lens). (FURIN 抗体 (AA 120-370))

Immunohistochemistry of paraffin-embedded human liver cancer using Furin antibody (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322) at dilution of 1:100 (40x lens). (FURIN 抗体 (AA 120-370))

IHC

Immunoprecipitation analysis of 300 μg extracts of HepG2 cells using 3 μg Furin antibody (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322). (FURIN 抗体 (AA 120-370))

Immunofluorescence analysis of cells using Furin Rabbit pAb (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322) at dilution of 1:150 (40x lens). (FURIN 抗体 (AA 120-370))

Immunofluorescence analysis of NIH-3T3 cells using Furin Rabbit pAb (ABIN6127933, ABIN6140815, ABIN6140817 and ABIN6223322) at dilution of 1:150 (40x lens). (FURIN 抗体 (AA 120-370))

6 images

产品编号 ABIN6140815

发货至: 中国

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中国
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Quick Overview for FURIN 抗体 (AA 120-370) (ABIN6140815)

抗原

See all FURIN 抗体

FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

适用

人

宿主

兔

克隆类型

多克隆

标记

This FURIN antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

抗原表位
15

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1
AA 120-370

序列

QQWYLSGVTQ RDLNVKAAWA QGYTGHGIVV SILDDGIEKN HPDLAGNYDP GASFDVNDQD PDPQPRYTQM NDNRHGTRCA GEVAAVANNG VCGVGVAYNA RIGGVRMLDG EVTDAVEARS LGLNPNHIHI YSASWGPEDD GKTVDGPARL AEEAFFRGVS QGRGGLGSIF VWASGNGGRE HDSCNCDGYT NSIYTLSISS ATQFGNVPWY SEACSSTLAT TYSSGNQNEK QIVTTDLRQK CTESHTGTSA S

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 120-370 of human Furin (NP_002560.1).

亚型

IgG
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 587-748) antibody
FURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 418-573) antibody
FURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (Internal Region) antibody
Verified FURIN 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 385-500) antibody
FURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 578-734) antibody
FURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 520-701) antibody
FURIN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibody
FURIN 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibody
FURIN 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1C3 unconjugated Recombinant Antibody

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 105-221) antibody
FURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (N-Term) antibody
FURIN 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

别名

FURIN

背景

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. Alternative splicing results in multiple transcript variants.,FURIN,FUR,PACE,PCSK3,SPC1,furin,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Ubiquitin,Notch Signaling Pathway,Endocrine & Metabolism,FURIN

分子量

86 kDa

基因ID

5045

UniProt

P09958

途径

Notch Signaling, Neurotrophin Signaling Pathway