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FOXO3 抗体 (AA 394-672)

This anti-FOXO3 antibody is a 兔 多克隆 antibody detecting FOXO3 in WB, IHC 和 IF. Suitable for 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN6140755
发货至: 中国

Quick Overview for FOXO3 抗体 (AA 394-672) (ABIN6140755)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

  • 125
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  • 1
小鼠

宿主

  • 125
  • 6
  • 1
  • 1

克隆类型

  • 110
  • 23
多克隆

标记

  • 79
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This FOXO3 antibody is un-conjugated

应用范围

  • 97
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 38
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 394-672

    序列

    ALPPSQPSPP GGLMQRGSSF PYTAKSSGLG SPTGSFNSTV FGPSSLNSLR QSPMQTIQEN RPATFSSVSH YGNQTLQDLL ASDSLSHSDV MMTQSDPLMS QASTAVSAQN ARRNVMLRND PMMSFAAQPT QGSLVNQNLL HHQHQTQGAL GGSRALSNSV SNMGLSDSSS LGSAKHQQQS PASQSMQTLS DSLSGSSLYS ASANLPVMGH DKFPSDLDLD MFNGSLECDM ESIIRSELMD ADGLDFNFDS LISTQNVVGL NVGNFTGAKQ ASSQSWVPG

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 394-672 of mouse FOXO3A (NP_062714.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

    Liu, Cai, Hu, Mei, Zhang, Ouyang, Wang, Zhang, Xiao: "Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)." in: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25692-25705, (2017) (PubMed).

    Yang, Wang, Xiong, Kong, Qiu, Shen, Huang: "Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 34, pp. 128-137, (2017) (PubMed).

  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FOXO3

    背景

    This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.,FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,G1/S Checkpoint,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,FOXO3

    分子量

    71 kDa

    基因ID

    56484

    UniProt

    Q9WVH4

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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