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FMR1 抗体 (AA 1-290)

This anti-FMR1 antibody is a 兔 多克隆 antibody detecting FMR1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6140718
发货至: 中国

Quick Overview for FMR1 抗体 (AA 1-290) (ABIN6140718)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FMR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-290

    序列

    MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPDR QIPFHDVRFP PPVGYNKDIN ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD ATYNEIVTIE RLRSVNPNKP ATKDTFHKIK LDVPEDLRQM CAKEAAHKDF KKAVGAFSVT YDPENYQLVI LSINEVTSKR AHMLIDMHFR SLRTKLSLIM RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN IQQARKVPGV TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human FMRP (NP_001172011.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    FMR1

    背景

    The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.,FMRP,FRAXA,POF,POF1,FMR1,POFX,Epigenetics & Nuclear Signaling,RNA Binding,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Dendrite marker,Synapse marker,FMR1

    分子量

    58 kDa/61 kDa/66 kDa/68 kDa/69 kDa/70 kDa/71 kDa

    基因ID

    2332

    UniProt

    Q06787

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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