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EWSR1 抗体 (AA 1-300)

This anti-EWSR1 antibody is a 兔 多克隆 antibody detecting EWSR1 in IF. Suitable for 人.
产品编号 ABIN6140352
发货至: 中国

Quick Overview for EWSR1 抗体 (AA 1-300) (ABIN6140352)

抗原

See all EWSR1 抗体
EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This EWSR1 antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    AA 1-300

    序列

    MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV SYTQAQTTAT YGQTAYATSY GQPPTGYTTP TAPQAYSQPV QGYGTGAYDT TTATVTTTQA SYAAQSAYGT QPAYPAYGQQ PAATAPTRPQ DGNKPTETSQ PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP MQPVTAPPSY PPTSYSSTQP TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY PPQTGSYSQA PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSMSGPDNR

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EWSR1 (NP_001156757.1).

    亚型

    IgG
  • 应用备注

    IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

    别名

    EWSR1

    背景

    This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.,EWSR1,EWS,EWS-FLI1,bK984G1.4,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,EWSR1

    分子量

    37 kDa/61 kDa/62 kDa/68 kDa

    基因ID

    2130

    UniProt

    Q01844
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