EP400 抗体 (AA 90-330)
Quick Overview for EP400 抗体 (AA 90-330) (ABIN6140195)
抗原
See all EP400 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-330
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序列
- TLAPLPLPSP TSPGFQFSAQ PRRFEHGSPS YIQVTSPLSQ QVQTQSPTQP SPGPGQALQN VRAGAPGPGL GLCSSSPTGG FVDASVLVRQ ISLSPSSGGH FVFQDGSGLT QIAQGAQVQL QHPGTPITVR ERRPSQPHTQ SGGTIHHLGP QSPAAAGGAG LQPLASPSHI TTANLPPQIS SIIQGQLVQQ QQVLQGPPLP RPLGFERTPG VLLPGAGGAA GFGMTSPPPP TSPSRTAVPP G
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:1000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EP400 (E1A Binding Protein P400 (EP400))
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别名
- EP400
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背景
- Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.,EP400,CAGH32,P400,TNRC12,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EP400
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分子量
- 331 kDa/335 kDa/339 kDa/343 kDa
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基因ID
- 57634
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UniProt
- Q96L91
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途径
- Chromatin Binding
抗原
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