Cortactin 抗体 (AA 214-513)
Our Local Distributor
北京 101111
Quick Overview for Cortactin 抗体 (AA 214-513) (ABIN6139243)
抗原
See all Cortactin (CTTN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 214-513
-
序列
- EYQGKTEKHE SQKDYVKGFG GKFGVQTDRQ DKCALGWDHQ EKLQLHESQK DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL FPANYVELRQ
-
交叉反应
- 人
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 214-513 of human Cortactin (NP_612632.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Cortactin (CTTN)
-
别名
- CTTN
-
背景
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.,CTTN,EMS1,cortactin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell Adhesion,Cytoskeleton,Microfilaments,Actins,CTTN
-
分子量
- 57 kDa/61 kDa/70 kDa
-
基因ID
- 2017
-
UniProt
- Q14247
-
途径
- MAPK Pathway
抗原
-