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Cortactin 抗体 (AA 214-513)

This anti-Cortactin antibody is a 兔 多克隆 antibody detecting Cortactin in WB. Suitable for 人.
产品编号 ABIN6139243
发货至: 中国

Quick Overview for Cortactin 抗体 (AA 214-513) (ABIN6139243)

抗原

See all Cortactin (CTTN) 抗体
Cortactin (CTTN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cortactin antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 214-513

    序列

    EYQGKTEKHE SQKDYVKGFG GKFGVQTDRQ DKCALGWDHQ EKLQLHESQK DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL FPANYVELRQ

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 214-513 of human Cortactin (NP_612632.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cortactin (CTTN)

    别名

    CTTN

    背景

    This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.,CTTN,EMS1,cortactin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell Adhesion,Cytoskeleton,Microfilaments,Actins,CTTN

    分子量

    57 kDa/61 kDa/70 kDa

    基因ID

    2017

    UniProt

    Q14247

    途径

    MAPK Pathway
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