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Exportin 2 抗体 (AA 50-150)

This anti-Exportin 2 antibody is a 兔 多克隆 antibody detecting Exportin 2 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6139091
发货至: 中国

Quick Overview for Exportin 2 抗体 (AA 50-150) (ABIN6139091)

抗原

See all Exportin 2 (CSE1L) 抗体
Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

适用

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宿主

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克隆类型

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多克隆

标记

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This Exportin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 50-150

    序列

    LEKSQDNVIK VCASVTFKNY IKRNWRIVED EPNKICEADR VAIKANIVHL MLSSPEQIQK QLSDAISIIG REDFPQKWPD LLTEMVNRFQ SGDFHVINGV L

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Exportin 2 (XPO2) (NP_001243064.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:100 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

    别名

    CSE1L

    背景

    Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.,CSE1L,CAS,CSE1,XPO2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,CSE1L

    分子量

    22 kDa/103 kDa/107 kDa/110 kDa

    基因ID

    1434

    UniProt

    P55060

    途径

    Protein targeting to Nucleus
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